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The mitochondrion is the principal site of oxidative phosphorylation in most organisms, including plants. This organelle shows morphological, functional, and phylogenetic diversity. The tremendous diversity of the proteins and regulatory factors that determine mitochondrial function makes its study an extremely challenging task. One of the biggest challenges in mitochondrial biology is to understand the mechanical response of the organelle to a wide range of environmental changes. In this review, we summarize our current understanding of the mechanical properties of the mitochondrion. We focus on changes in the mitochondrial outer membrane, its interactions with the cytoskeleton, and how these processes relate to the assembly and integrity of the organelle.The relationship between cataract grading and posterior capsule opacification in the bag after cataract surgery.
To analyse the relationship between cataract grades and posterior capsule opacification (PCO) after cataract surgery. Retrospective non-randomized clinical study at Chindia Eye Hospital, Bengaluru, India. 506 eyes that had clear lens extraction with posterior chamber intraocular lens implantation were reviewed. There were 280 (55.2%) males and 226 (44.8%) females. The mean age was 62.15±9.27 years. A serial section technique was used to grade the cataract. The lenses were evaluated for capsular opacification in 2.5 mm diameter spots after 1, 3, 6 and 12 months. The grading of the cataract and the PCO was correlated with the age and sex of the patients. The rate of PCO increases with age and also with the severity of cataract (p
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